4-Chloro-3-hydroxyisothiazole-5-carboxylic acid CAS 948292-12-4
| CAS No. | 948292-12-4 |
| Molecular Formula | C4H2ClNO3S |
| Molecular Weight | 179.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Chloro-3-hydroxyisothiazole-5-carboxylic acid (CAS 948292-12-4) is a high-purity analytical reference standard with the molecular formula C4H2ClNO3S and a molecular weight of 179.58 g/mol.
Structurally, 4-Chloro-3-hydroxyisothiazole-5-carboxylic acid (C4H2ClNO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 179.58 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Chloro-3-hydroxyisothiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2ClNO3S |
| Molecular Weight | 179.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 5-Amino-6-chloro-2,3-dicyanopyrazine (CAS 56413-96-8)
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- 7-Chloroindole-3-carbaldehyde (CAS 1008-07-7)
- 2H-Pyrazolo[4,3-d]pyrimidine-3-carbonitrile, 5-chloro- (CAS 2092193-29-6)
- 1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 103058-60-2)
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- 2,2-Diethyl-6-methoxy-3,4-dihydronaphthalen-1(2H)-one (CAS 149456-21-3)
- tert-Butyl 2-oxo-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 906647-95-8)
- Fudosteine Impurity 11 (CAS CATO-C4X-144711)
- 1713163-00-8 7-Bromo-4-methoxy-3-hydroxyindoline (CAS 1713163-00-8)
- 4-Cyano-N-{[2-methoxy-6-(1H-pyrrol-1-yl)phenyl]methyl}benzamide (CAS 866042-94-6)
- Benzyl (4-((2-hydroxyethyl)amino)cyclohexyl)(isopropyl)carbamate (CAS 1353961-54-2)
- 3-(3,4-Difluorophenyl)cyclohexan-1-one (CAS 1342443-62-2)
- Semaglutide impurity 50 (CAS 2773558-66-8)
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