Furosemide Impurity 44 CAS CATO-C4X-140244

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-140244
Molecular FormulaC8H6Cl2O5S
Molecular Weight285.10 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Furosemide Impurity 44 CAS CATO-C4X-140244 chemical structure

Description

As a certified reference material (CRM), Furosemide Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Furosemide Impurity 44 (CAS CATO-C4X-140244) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6Cl2O5S and a molecular weight of 285.10 g/mol.

The molecular framework of Furosemide Impurity 44 (C8H6Cl2O5S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC8H6Cl2O5S
Molecular Weight285.10 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Sulfur Atoms1

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