Rimegepant Impurity 51 CAS 1289023-89-7
| CAS No. | 1289023-89-7 |
| Molecular Formula | C16H13F2NO2 |
| Molecular Weight | 289.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Rimegepant Impurity 51 (CAS 1289023-89-7), a pharmacopoeial impurity reference standard (molecular formula C16H13F2NO2, MW 289.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Rimegepant Impurity 51 (C16H13F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13F2NO2 |
| Molecular Weight | 289.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Rimegepant Standards
- Rimegepant Impurity 134 (CAS CATO-C4X-2487134)
- Rimegepant Impurity 126 (CAS CATO-C4X-2487126)
- Rimegepant Impurity 101 (CAS CATO-C4X-2487101)
- Rimegepant Impurity 124 (CAS CATO-C4X-2487124)
- Rimegepant Impurity 128 (CAS CATO-C4X-2487128)
- Rimegepant Impurity 38 (CAS 1373116-05-2)
- Rimegepant Impurity 48 (CAS CATO-C4X-248748)
- Rimegepant Impurity 49 (CAS CATO-C4X-248749)
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- Mianserin Impurity 103 (CAS 745757-89-5)
- N-(3-chloro-4-fluorophenyl)tetrahydro-2H-thiopyran-3-amine (CAS 1342164-47-9)
- Ethyl 2-(diisopropoxyphosphoryl)-2-fluoroacetate (CAS 110624-86-7)
- N1-benzyl-5-fluorobenzene-1,2-diamine (CAS 1250244-09-7)
- 5,6,7,8-Tetrahydronaphthalene-1,2-diol (CAS 6255-90-9)
- 1-(5-(O-tolyl)-1,3,4-oxadiazol-2-yl)ethan-1-amine hydrochloride (CAS 1417634-16-2)
- 4-(2-Hydroxypropan-2-yl)cyclohexane-1-carboxylic acid (CAS 91006-79-0)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
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