Enzalutamide Impurity N2 CAS 1289942-66-0
| CAS No. | 1289942-66-0 |
| Molecular Formula | C12H15FN2O3 |
| Molecular Weight | 254.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Enzalutamide Impurity N2 (C12H15FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Enzalutamide Impurity N2 (CAS 1289942-66-0), a pharmacopoeial impurity reference standard (molecular formula C12H15FN2O3, MW 254.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15FN2O3 |
| Molecular Weight | 254.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Enzalutamide Standards
- Enzalutamide Impurity 54 (CAS CATO-C4X-101654)
- Enzalutamide Impurity 15 (CAS 1895865-10-7)
- Enzalutamide Impurity 37 (CAS 1705583-65-8)
- Enzalutamide Impurity 36 (CAS CATO-C4X-101636)
- Enzalutamide Impurity 46 (CAS CATO-C4X-101646)
- Enzalutamide Impurity 6 (CAS 1332524-02-3)
- Enzalutamide Impurity 45 (CAS 1332524-01-2)
- Enzalutamide Impurity 7 (CAS 1802242-47-2)
Recommended Standards
- (1-(3-Fluoro-2-nitrophenyl)piperidin-3-yl)methanol (CAS 1252463-51-6)
- 3-Fluoro-4-(quinolin-4-yloxy)aniline (CAS 1308641-96-4)
- 2-(1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-5-yl)acetic acid (CAS 1246761-51-2)
- 2-(4-Cyanobenzenesulfonamido)propanoic acid (CAS 1308963-00-9)
- Eltrombopag Impurity 44 (CAS 1782285-05-5)
- Esomeprazole Impurity 32 (CAS 2080-75-3)
- Melphalan EP Impurity I (CAS 573704-40-2)
- 3-(3-Bromo-4-fluorophenyl)-3-methylbutan-2-one (CAS 1239964-09-0)
- Progesterone Impurity 23 (CAS 21063-91-2)
- 3-Cyanoquinoline 1-oxide (CAS 63124-13-0)
- 1-(Bromomethyl)-1-((4-methylpentan-2-yl)oxy)cyclohexane (CAS 1249486-04-1)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-hydroxypyridine-5-acetonitrile (CAS 1805607-64-0)
- 5,6,7,8-Tetrahydro-3H-isochromen-3-one (CAS 6249-20-3)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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