Esomeprazole Impurity 32 CAS 2080-75-3
| CAS No. | 2080-75-3 |
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Esomeprazole Impurity 32 (CAS 2080-75-3, C8H8N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Esomeprazole Impurity 32 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 164.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Esomeprazole Standards
- Esomeprazole Impurity 106 (CAS 110464-72-7)
- Esomeprazole Impurity 97 (CAS 142885-88-9)
- Esomeprazole Impurity 39 (CAS 92806-98-9)
- Esomeprazole Impurity 105 (CAS 86604-78-6)
- Esomeprazole Impurity 115 (CAS 1424857-83-9)
- Esomeprazole Impurity 40 (CAS 86604-80-0)
- Esomeprazole Impurity 28 (CAS 577-72-0)
- Esomeprazole Impurity 44 (CAS 16133-49-6)
Recommended Standards
- 3,4-Methylenedioxyacetophenone (CAS 3162-29-6)
- Olaparib Impurity 60 (CAS CATO-C4X-113560)
- cis-Norbornene-exo-2,3-dicarboxylic Anhydride (CAS 2746-19-2)
- Olaparib Impurity 80 (CAS 4122-56-9)
- Benserazide Impurity 19 (CAS 487-70-7)
- Nafamostat Impurity 63 (CAS 121714-82-7)
- Regadenoson Impurity 54 (CAS CATO-C4X-198554)
- Hydantoin Impurity 12 (CAS 113586-23-5)
- (R)-Benzyl 5-(hydroxymethyl)-2,2-dimethylmorpholine-4-carboxylate (CAS 1263078-09-6)
- 2-(2,6-Dimethylpyridin-4-yl)ethan-1-amine (CAS 1023817-37-9)
- Dimethyl 2-Methyl-3-oxosuccinate (CAS 63921-06-2)
- 2-Amino-4-methoxy-6-methylpyrimidine (CAS 7749-47-5)
- 3-Amino-4-(4-bromophenyl)-1-methylpyrazole (CAS 1782569-25-8)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
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