Darunavir Impurity 20 CAS 2307745-62-4
| CAS No. | 2307745-62-4 |
| Molecular Formula | C34H53N3O6 |
| Molecular Weight | 599.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Darunavir Impurity 20.
As a process- or degradation-related impurity, Darunavir Impurity 20 (CAS 2307745-62-4, C34H53N3O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C34H53N3O6, Darunavir Impurity 20 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 599.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H53N3O6 |
| Molecular Weight | 599.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
Related Darunavir Standards
Recommended Standards
- Nelfinavir sulfone, >98% (CAS 1041389-29-0)
- Fmoc-D-Homocys(Trt)-OH (CAS 1007840-62-1)
- Arotinolol Impurity 23 (CAS CATO-C4X-185423)
- n-(3-(Azepan-1-ylsulfonyl)phenyl)-2-((3-(3-morpholinopropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetamide (CAS 749889-38-1)
- Gadoxetate impurity 21 (CAS CATO-C4X-261821)
- N-Nitroso Aceclofenac EP Impurity A (CAS 66505-80-4)
- Lusutrombopag Impurity 65 (CAS CATO-C4X-208465)
- 2-Iodo-6-(trifluoromethyl)nicotinic acid (CAS 1806585-48-7)
- 6-(3,4-Dimethylphenyl)-3-(piperidin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706432-95-2)
- N-(7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-3-yl)cyclopropanecarboxamide (CAS 1382848-03-4)
- N-[3,5-bis(trifluoromethyl)phenyl]-2,6-difluoro-3-nitrobenzamide (CAS 260554-68-5)
- Fmoc-Asp(ODmab)-OH (CAS 269066-08-2)
- 3-(2,4-Dichloro-5-fluorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618382-97-1)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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