Pioglitazone Thiazolidinedione Ring-opened N-β-D-Glucuronide CAS 1296832-76-2
| CAS No. | 1296832-76-2 |
| Molecular Formula | C25H30N2O10S |
| Molecular Weight | 550.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Pioglitazone Thiazolidinedione Ring-opened N-β-D-Glucuronide (CAS 1296832-76-2), molecular formula C25H30N2O10S and molecular weight 550.58 g/mol, is a CATO reference standard with documented purity and traceability.
Pioglitazone Thiazolidinedione Ring-opened N-β-D-Glucuronide (C25H30N2O10S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H30N2O10S |
| Molecular Weight | 550.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone N-beta-D-Glucuronide (Mixture of Diastereomers) (CAS 1296832-75-1)
- Pioglitazone EP Impurity G (CAS 952187-99-4)
- Pioglitazone impurity 29 (CAS CATO-C4X-138329)
- Pioglitazone EP Impurity C (CAS 952188-00-0)
- Pioglitazone impurity 52 (CAS CATO-C4X-138352)
- Pioglitazone impurity 57 (CAS 1147527-36-3)
- Pioglitazone Impurity 2 (CAS CATO-C4X-13832)
- Pioglitazone impurity 01 (CAS 1229114-67-3)
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