Pioglitazone EP Impurity C CAS 952188-00-0
| CAS No. | 952188-00-0 |
| Molecular Formula | C28H31N3O3S |
| Molecular Weight | 489.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Pioglitazone EP Impurity C (CAS 952188-00-0), a pharmacopoeial impurity reference standard (molecular formula C28H31N3O3S, MW 489.63 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Pioglitazone EP Impurity C (C28H31N3O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pioglitazone EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H31N3O3S |
| Molecular Weight | 489.63 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone impurity 52 (CAS CATO-C4X-138352)
- Pioglitazone impurity 57 (CAS 1147527-36-3)
- Pioglitazone Impurity 2 (CAS CATO-C4X-13832)
- Pioglitazone impurity 29 (CAS CATO-C4X-138329)
- Pioglitazone N-beta-D-Glucuronide (Mixture of Diastereomers) (CAS 1296832-75-1)
- Pioglitazone impurity 26 (CAS 446052-43-3)
- Pioglitazone Thiazolidinedione Ring-opened N-β-D-Glucuronide (CAS 1296832-76-2)
- Pioglitazone EP Impurity F (CAS 1391052-15-5)
Recommended Standards
- Tofacitinib Impurity 64 (CAS 2504210-40-4)
- Nirogacestat (CAS 1290543-63-3)
- Tofacitinib Impurity 56 (CAS 923036-30-0)
- (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(((tert-butyldiphenylsilyl)oxy)methyl)tetrahydrofuran-3-ol (CAS 129835-18-3)
- Glucosamine EP Impurity C (CAS 17460-13-8)
- Naproxen Impurity 36 (CAS CATO-C4X-170836)
- Pilocarpine Impurity 21 (CAS CATO-C4X-240121)
- Indole-3-propyl Phosphate (CAS 40716-80-1)
- Methyl 2-acetamido-3-nitrobenzoate (CAS 95067-27-9)
- Ethyl 1-(2-(3-cyanophenyl)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxylate (CAS 1432436-39-9)
- 1-(Difluoromethyl)-3-iodopyridin-2(1H)-one (CAS 2092680-07-2)
- Cyclohex-3-en-1-yl(piperazin-1-yl)methanone (CAS 64579-65-3)
- (R)-1-benzyl-3,3-difluoro-4-hydroxypyrrolidin-2-one (CAS 1914929-31-9)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com