Perindopril EP Impurity D CAS 130061-28-8
| CAS No. | 130061-28-8 |
| Molecular Formula | C17H26N2O4 |
| Molecular Weight | 322.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 322.40 g/mol gives Perindopril EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Perindopril EP Impurity D (CAS 130061-28-8), a pharmacopoeial impurity reference standard (molecular formula C17H26N2O4, MW 322.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Perindopril EP Impurity D is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Perindopril EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H26N2O4 |
| Molecular Weight | 322.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 2 |
Related Perindopril Standards
- Perindopril EP Impurity C (CAS 129970-99-6)
- Perindopril Impurity 101 (CAS CATO-C4X-1252101)
- Perindopril Impurity 97 (CAS CATO-C4X-125297)
- Perindopril Impurity 42 (CAS CATO-C4X-125242)
- Perindopril EP Impurity B (CAS 95153-31-4)
- Perindopril Impurity 99 (CAS 145513-63-9)
- Perindopril Impurity 102 (CAS 952108-77-9)
- Perindopril EP Impurity B-d4 (CAS 1356841-18-3)
Recommended Standards
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