Perindopril EP Impurity B-d4 CAS 1356841-18-3
| CAS No. | 1356841-18-3 |
| Molecular Formula | - |
| Molecular Weight | 344.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 344.44 g/mol gives Perindopril EP Impurity B-d4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Perindopril EP Impurity B-d4 (CAS 1356841-18-3) is a certified pharmaceutical impurity reference standard with the molecular formula C17H24D4N2O5 and a molecular weight of 344.44 g/mol.
The molecular framework of Perindopril EP Impurity B-d4 (C17H24D4N2O5) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Perindopril EP Impurity B-d4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H24D4N2O5 |
| Molecular Weight | 344.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Perindopril Standards
- Perindopril EP Impurity B (CAS 95153-31-4)
- Perindopril Impurity 99 (CAS 145513-63-9)
- Perindopril EP Impurity F (CAS 129970-98-5)
- Perindopril Impurity 42 (CAS CATO-C4X-125242)
- Perindopril EP impurity M (CAS CATO-C4X-125277)
- Perindopril Impurity 101 (CAS CATO-C4X-1252101)
- Perindopril EP Impurity D (CAS 130061-28-8)
- Perindopril EP Impurity C (CAS 129970-99-6)
Recommended Standards
- 620-68-8 Z9J25OS07L Glycerol trivalerate Pentanoic acid, 1,2,3-propanetriyl ester Propane-1,2,3-triyl trivalerate EINECS 210-648-8 UNII-Z9J25OS07L (CAS 620-68-8)
- Hydrocortisone Impurity 31 (CAS 10184-70-0)
- Propane-1,2,3-triyl tris(3-methylbutanoate) (CAS 620-63-3)
- Hydrocortisone (E)-17-Deoxyaldehyde Derivative (CAS 105562-12-7)
- Mivacurium chloride Impurity 78 (CAS CATO-C4X-137578)
- Atogepant Impurity 56 (CAS CATO-C4X-328556)
- Bortezomib Impurity 31 (CAS 1608986-16-8)
- (Z)-3-Methylpyrazine-2-carbaldehyde oxime (CAS 910824-80-5)
- 4-oxo-4-(pyridin-2-yl)butanoic acid hydrochloride (CAS 1803606-28-1)
- Bis(1,3-dimethylcyclopenta-2,4-dien-1-yl)zirconium(IV) chloride (CAS 119445-92-0)
- 5-Nonyl-2-(4-(nonyloxy)phenyl)pyrimidine (CAS 99895-85-9)
- Tapentadol impurity 7 (CAS 387356-03-8)
- 2-Chloro-1-methoxy-4-methyl-3-nitro-benzene (CAS 1807173-28-9)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com