Paroxetine EP Impurity D HCl CAS 130855-30-0
| CAS No. | 130855-30-0 |
| Molecular Formula | C19H20FNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Paroxetine EP Impurity D HCl (CAS 130855-30-0), a pharmacopoeial impurity reference standard (molecular formula C19H20FNO3HCl, MW 365.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Paroxetine EP Impurity D HCl (C19H20FNO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 365.83 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H20FNO3 HCl |
| Molecular Weight | 365.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Ruxolitinib Impurity 25 (CAS CATO-C4X-205825)
- Avanafil Impurity 70 (CAS 32897-26-0)
- Tolvaptan Impurity 41 (CAS 1580889-32-2)
- Diethyl 2-Ethyl-2-acetamidomalonate (CAS 32819-24-2)
- (1-(5-Methylisoxazol-3-yl)cyclopentyl)methanamine (CAS 1352505-64-6)
- 2-Bromo-3-methylbenzofuran (CAS 38281-48-0)
- 2-(Aminomethyl)benzo[d]oxazole-4-acetonitrile (CAS 1804411-53-7)
- 5-Bromo-N-cyclohexyl-N-ethylpyridin-2-amine (CAS 1220038-76-5)
- 2-Ethyl-3-(trifluoromethyl)phenol (CAS 1243453-24-8)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com