Metoprolol Impurity 10 CAS 131564-70-0
| CAS No. | 131564-70-0 |
| Molecular Formula | C14H23NO3 |
| Molecular Weight | 253.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Metoprolol Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Metoprolol Impurity 10 (CAS 131564-70-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H23NO3 and a molecular weight of 253.34 g/mol.
Based on its molecular formula C14H23NO3, Metoprolol Impurity 10 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 253.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H23NO3 |
| Molecular Weight | 253.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 1 |
Related Metoprolol Standards
- Metoprolol EP Impurity A (CAS 109632-08-8)
- Metoprolol EP Impurity H (CAS 62572-94-5)
- Metoprolol Impurity 47 (CAS CATO-C4X-136747)
- Metoprolol USP Related Compound B (CAS 56718-76-4)
- Metoprolol Impurity 51 (CAS 2517349-25-4)
- Metoprolol impurity 1 (CAS 150332-88-0)
- Metoprolol Impurity 2 (Mixture of Z and E Isomers) (CAS 82961-02-2)
- Metoprolol Impurity 44 (CAS CATO-C4X-136744)
Recommended Standards
- Formoterol Impurity 95 (CAS CATO-C4X-152595)
- Betaxolol Impurity 9 (CAS 131564-69-7)
- Mianserin Impurity 53 (CAS CATO-C4X-136953)
- Oseltamivir Impurity 164 (CAS 204255-02-7)
- Obeticholic Acid Impurity 35 (CAS CATO-C4X-115335)
- Paliperidone Impurity 41 (CAS CATO-C4X-172441)
- Folic Acid EP Impurity C (CAS 47707-78-8)
- (2-Chloroethanesulfonyl)ethene (CAS 7327-58-4)
- n-(3-Methoxypropyl)-3-nitropyridin-2-amine (CAS 931751-65-4)
- 5-(Trifluoromethyl)pyrazine-2-carbaldehyde (CAS 1196151-36-6)
- Boc-Dap(ivDde)-OH (CAS 1313054-38-4)
- N-(4-hydroxyphenyl)cyclopropanecarboxamide (CAS 14372-30-6)
- (Z)-2-Chloro-2-butene (CAS 2211-69-0)
- Semaglutide Impurity 75 (CAS CATO-C4X-2226175)
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