Naltrexone Hydrochloride EP Impurity C CAS 131670-05-8
| CAS No. | 131670-05-8 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Naltrexone Hydrochloride EP Impurity C (CAS 131670-05-8), a pharmacopoeial impurity reference standard (molecular formula C20H23NO4HCl, MW 377.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H23NO4HCl, Naltrexone Hydrochloride EP Impurity C contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 377.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Naltrexone Hydrochloride EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 HCl |
| Molecular Weight | 377.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Naltrexone Standards
- Naltrexone EP Impurity A (CAS 1007856-83-8)
- Naltrexone Impurity 23 (CAS 102272-79-7)
- Naltrexone Impurity 15 (CAS 111129-14-7)
- Naltrexone impurity 30 (CAS 112242-13-4)
- Naltrexone Impurity 19 (CAS 112269-62-2)
- Naltrexone Impurity 13 (CAS 1201-90-7)
- Naltrexone Impurity 11 (CAS 123086-68-0)
- Naltrexone-D3 (CAS 1261080-26-5)
Recommended Standards
- Agomelatine Impurity 11 (CAS 138113-07-2)
- Fudosteine Impurity 40 (CAS CATO-C4X-144740)
- Roxadustat Impurity 117 (CAS CATO-C4X-2213117)
- Ethyl (E)-2-cyano-3-(3,5-dibromo-4-hydroxyphenyl)acrylate (CAS 773089-21-7)
- 2-Acetamido-6-(methylthio)hexanoic acid (CAS 1956317-91-1)
- 2-Amino-N-(furan-2-ylmethyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide (CAS 588692-33-5)
- (2S)-2-(((9H-fluoren-9-yl)methoxy)carbonyl)-5,5,5-trifluoro-4-methylpentanoic acid 777946-04-0 A13354 Fmoc-D,L-5,5,5-trifluoroleucine (CAS 777946-04-0)
- 2-(3-(Difluoromethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 627526-04-9)
- N-(2,6-dichloro-4-sulfamoylphenyl)propanamide (CAS 1094361-88-2)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com