Docetaxel Impurity 24 CAS 132201-32-2
| CAS No. | 132201-32-2 |
| Molecular Formula | C9H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 217.65 g/mol gives Docetaxel Impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Docetaxel Impurity 24 (CAS 132201-32-2) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11NO3HCl and a molecular weight of 217.65 g/mol.
Based on its molecular formula C9H11NO3HCl, Docetaxel Impurity 24 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 217.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Docetaxel Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11NO3 HCl |
| Molecular Weight | 217.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Docetaxel Standards
- Docetaxel Impurity 10 (O-BOC N-pyruvy ldocetaxel) (CAS 1021489-55-3)
- Docetaxel Impurity 85 (CAS 1095547-79-7)
- Docetaxel Impurity 49 (CAS 1095547-86-6)
- Docetaxel Impurity 48 (CAS 1095547-90-2)
- Docetaxel Impurity 34 (CAS 1095547-96-8)
- Docetaxel Impurity 35 (CAS 1095547-98-0)
- Docetaxel Impurity 36 (CAS 110258-92-9)
- Docetaxel Impurity 32 (CAS 1112457-40-5)
Recommended Standards
- Cefotaxime Impurity 71 (CAS CATO-C4X-120171)
- Prednisolone impurity 66 (CAS 137759-50-3)
- Lodoxamide lmpurity 18 (CAS 67451-36-9)
- 3-Nitro-5-(trifluoromethyl)phenol (CAS 349-57-5)
- Avanafil Impurity N91 (CAS 31519-62-7)
- (3-((3,4-Dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid (CAS 139667-74-6)
- (R)-(1-ethylpyrrolidin-2-yl)methanol (CAS 79802-13-4)
- 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one 4-methylbenzenesulfonate (CAS 952340-39-5)
- (1S,4R,6R)-tert-Butyl 6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1628319-90-3)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
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