Sofosbuvir 3,5-Bis-(S)-phosphate CAS 1337482-17-3
| CAS No. | 1337482-17-3 |
| Molecular Formula | C34H47FN4O13P2 |
| Molecular Weight | 800.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Sofosbuvir 3,5-Bis-(S)-phosphate (CAS 1337482-17-3), molecular formula C34H47FN4O13P2 and molecular weight 800.70 g/mol, is a CATO reference standard with documented purity and traceability.
Sofosbuvir 3,5-Bis-(S)-phosphate (C34H47FN4O13P2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H47FN4O13P2 |
| Molecular Weight | 800.70 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 42 (CAS CATO-C4X-105242)
- Sofosbuvir Impurity 55 (CAS CATO-C4X-105255)
- Sofosbuvir Impurity 78 (CAS CATO-C4X-105278)
- Sofosbuvir Impurity 83 (CAS CATO-C4X-105283)
- Sofosbuvir Impurity 52 (CAS CATO-C4X-105252)
- Sofosbuvir Impurity 56 (CAS 1496551-70-2)
- Sofosbuvir Impurity 88 (CAS 30361-19-4)
- Sofosbuvir Impurity 10 (CAS CATO-C4X-105210)
Recommended Standards
- N-{4-[4-({[3-(2,3,4,5,6-pentafluorophenoxy)anilino]carbonyl}amino)benzyl]phenyl}-N'-[3-(2,3,4,5,6-pentafluorophenoxy)phenyl]urea (CAS 333408-54-1)
- Jionoside A1 (CAS 120444-60-2)
- Macitentan Impurity 13 (CAS 2089065-77-8)
- Tenofovir Impurity 83 (CAS CATO-C4X-107683)
- Methyl 4-aminocyclohexane-1-carboxylate (CAS 175867-59-1)
- 2-[4-(4-chlorophenyl)piperazin-1-yl]-4-methoxypyridine-3-carbonitrile 339016-80-7 7M-049 (CAS 339016-80-7)
- 2-(2,2-Dimethylpropanamido)-3-hydroxybutanoic acid (CAS 32909-48-1)
- 3-(Hydroxymethyl)-3-methylpyrrolidin-2-one (CAS 1781900-40-0)
- 5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyridine-7-carboxylic acid (CAS 1508614-13-8)
- Ethyl 5-chloro-2-methoxybenzoate (CAS 68216-06-8)
- 1-Cyclopropyl-1H-1,2,3-triazole-5-carbaldehyde (CAS 1782544-86-8)
- spiro[cyclopropane-2,1-tetralin]-1-carboxylic acid (CAS 1248314-77-3)
- 3-(1-Methyl-1H-pyrrol-2-yl)-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole hydrochloride (CAS 1638612-57-3)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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