Macitentan Impurity 13 CAS 2089065-77-8
| CAS No. | 2089065-77-8 |
| Molecular Formula | C28H32Br2N8O6S2 |
| Molecular Weight | 800.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Macitentan Impurity 13 (C28H32Br2N8O6S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Macitentan Impurity 13 (CAS 2089065-77-8), a pharmacopoeial impurity reference standard (molecular formula C28H32Br2N8O6S2, MW 800.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Macitentan Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H32Br2N8O6S2 |
| Molecular Weight | 800.54 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 2 |
Related Macitentan Standards
- Macitentan Impurity 5 (CAS CATO-C4X-11755)
- Macitentan impurity 29 (CAS CATO-C4X-117529)
- Macitentan Impurity 47 (CAS CATO-C4X-117547)
- Macitentan Impurity 22 (CAS CATO-C4X-117522)
- Macitentan Impurity 23 (CAS CATO-C4X-117523)
- Macitentan Impurity 27 (CAS CATO-C4X-117527)
- Macitentan Impurity 43 (CAS CATO-C4X-117543)
- Macitentan-d4 (CAS 1258428-05-5)
Recommended Standards
- Dotinurad Impurity 238 (CAS CATO-C4X-2494238)
- N-{4-[4-({[3-(2,3,4,5,6-pentafluorophenoxy)anilino]carbonyl}amino)benzyl]phenyl}-N'-[3-(2,3,4,5,6-pentafluorophenoxy)phenyl]urea (CAS 333408-54-1)
- 3,5-Bis(perfluorohexyl)-1-(trifluoroacetyl)-1H- pyrazole (CAS 261761-08-4)
- Sofosbuvir 3,5-Bis-(S)-phosphate (CAS 1337482-17-3)
- Dalbavancin Impurity 57 (CAS CATO-C4X-160257)
- Edoxaban Impurity 114 (CAS CATO-C4X-1063114)
- Urapidil Impurity 89 (CAS CATO-C4X-192489)
- 2-(2-Chloroethyl)-6-fluoro-1H-benzimidazole 3102AF 915923-27-2 C9H8ClFN2 (CAS 915923-27-2)
- 2-((2-Fluorophenoxy)methyl)piperidine (CAS 883541-43-3)
- 4-(4-methylphenyl)piperidine-4-carboxylic acid hydrochloride (CAS 1803596-15-7)
- 3-Methoxypropanethioamide (CAS 1016740-19-4)
- 1-(4-Amino-2-fluorophenyl)-N,N-dimethylpiperidin-4-amine (CAS 1154665-52-7)
- 2-(Dibenzo[b,d]furan-3-yloxy)ethanamine (CAS 193761-41-0)
- Semaglutide Impurity 149 (CAS CATO-C4X-2226149)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com