Isavuconazole impurity 70 CAS CATO-C4X-1236170
| CAS No. | CATO-C4X-1236170 |
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isavuconazole impurity 70.
CATO supplies Isavuconazole impurity 70 (CAS CATO-C4X-1236170), a pharmacopoeial impurity reference standard (molecular formula C12H13F2N3O2, MW 269.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Isavuconazole impurity 70 (C12H13F2N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 269.25 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Isavuconazole impurity 70 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Isavuconazole Standards
- Isavuconazole impurity 68 (CAS CATO-C4X-1236168)
- Isavuconazole impurity 69 (CAS CATO-C4X-1236169)
- Isavuconazole impurity 72 (CAS CATO-C4X-1236172)
- Isavuconazole impurity 66 (CAS CATO-C4X-1236166)
- Isavuconazole Impurity 213 (CAS CATO-C4X-1236213)
- Isavuconazole Impurity 107 (CAS CATO-C4X-1236107)
- Isavuconazole Impurity 110 (CAS CATO-C4X-1236110)
- Isavuconazole Impurity 113 (CAS CATO-C4X-1236113)
Recommended Standards
- Efinaconazole Impurity 12 (CAS 133775-25-4)
- Efinaconazole Impurity 3 (CAS 135272-36-5)
- Propargyl-PEG2-NHS ester (CAS 2512228-06-5)
- Efinaconazole Impurity 37 (CAS CATO-C4X-124337)
- Luliconazole Impurity 10 (CAS 229334-55-8)
- Nirmatrelvir Impurity 8 (CAS 2889532-78-7)
- Carbidopa Impurity 30 (CAS CATO-C4X-231030)
- 5-Bromo-1-(methylthio)-1,6-dihydropyrimidine (CAS 14001-67-4)
- 2-(4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methylpropanenitrile (CAS 2820542-43-4)
- 5-Azaspiro[2.4]heptane-4,7-dione (CAS 1643666-96-9)
- (methyl{[(3-nitrophenyl)amino]carbonyl}amino)acetic acid (CAS 1040320-73-7)
- 2,2'-(Octanedioylbis(oxy))bis(N,N,N-trimethylethan-1-aminium) iodide (CAS 3810-71-7)
- Budesonide Impurity 64 (CAS 69155-84-6)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com