Efinaconazole Impurity 5 CAS 135270-11-0
| CAS No. | 135270-11-0 |
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 269.25 g/mol gives Efinaconazole Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Efinaconazole Impurity 5 (CAS 135270-11-0), a pharmacopoeial impurity reference standard (molecular formula C12H13F2N3O2, MW 269.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Efinaconazole Impurity 5 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Efinaconazole Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Efinaconazole Standards
- Efinaconazole Impurity 12 (CAS 133775-25-4)
- Efinaconazole Impurity 3 (CAS 135272-36-5)
- Efinaconazole Impurity 37 (CAS CATO-C4X-124337)
- Efinaconazole Impurity 4 (CAS 135270-05-2)
- Efinaconazole Impurity 7 (CAS CATO-C4X-12437)
- Efinaconazole Impurity 9 (CAS CATO-C4X-12439)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Efinaconazole Impurity 27 (CAS 136081-74-8)
Recommended Standards
- Meropenem Impurity 10 (CAS 1562123-84-5)
- Benserazide Impurity 58 (CAS CATO-C4X-142758)
- Isavuconazole impurity 70 (CAS CATO-C4X-1236170)
- Paliperidone Impurity 153 (CAS CATO-C4X-1724153)
- Abemaciclib Impurity 51 (CAS CATO-C4X-293751)
- Nemonoxacin Impurity 23 (CAS CATO-C4X-312823)
- LCZ-696 Impurity 80 (CAS 128779-47-5)
- (4-Fluoropyridin-3-yl)methanamine hydrochloride (CAS 1391733-71-3)
- 1,3,5-Trimethyl-2-nitrobenzene (CAS 603-71-4)
- n-Carbamoyl-2-((3-ethynylphenyl)amino)acetamide (CAS 1020933-52-1)
- 2-Cyclopropoxy-1-isopropoxy-4-nitrobenzene (CAS 1243373-43-4)
- 2-(Propan-2-yl)-1,3-thiazole-4-carbonitrile (CAS 848555-18-0)
- 1,1-Diethylguanidine acetate (CAS 1208081-42-8)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com