Efinaconazole Impurity 37 CAS CATO-C4X-124337
| CAS No. | CATO-C4X-124337 |
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 269.25 g/mol gives Efinaconazole Impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Efinaconazole Impurity 37 (CAS CATO-C4X-124337, C12H13F2N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Efinaconazole Impurity 37 (C12H13F2N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Efinaconazole Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13F2N3O2 |
| Molecular Weight | 269.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Efinaconazole Standards
- Efinaconazole Impurity 12 (CAS 133775-25-4)
- Efinaconazole Impurity 3 (CAS 135272-36-5)
- Efinaconazole Impurity 4 (CAS 135270-05-2)
- Efinaconazole Impurity 5 (CAS 135270-11-0)
- Efinaconazole Impurity 7 (CAS CATO-C4X-12437)
- Efinaconazole Impurity 9 (CAS CATO-C4X-12439)
- Efinaconazole Impurity 35 (CAS 127001-03-0)
- Efinaconazole Impurity 27 (CAS 136081-74-8)
Recommended Standards
- Isavuconazole impurity 70 (CAS CATO-C4X-1236170)
- Isavuconazole impurity 69 (CAS CATO-C4X-1236169)
- Isavuconazole impurity 68 (CAS CATO-C4X-1236168)
- Meropenem Impurity 10 (CAS 1562123-84-5)
- Ledipasvir Impurity 17 (CAS CATO-C4X-331317)
- Canagliflozin Impurity 113 (CAS 2639148-37-9)
- Hydrochlorothiazide Impurity 29 (CAS 1753-71-5)
- 3-Chloro-N-(4-fluorobenzyl)benzo[b]thiophene-2-carboxamide (CAS 162091-01-2)
- N,N-Dinitroso Valsartan Desvaleryl Impurity 86 (CAS CATO-C4X-105786)
- Ethyl 3,5-dimethylisonicotinate (CAS 1256561-29-1)
- N-methyl-1-(5-methyl-1-phenyl-1H-pyrazol-4-yl)methanamine (CAS 1031843-22-7)
- 5-Chloro-3-((4-chlorophenyl)thio)-2-methyl-1H-indole (CAS 628736-22-1)
- 1-(3-phenylpropyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1909327-37-2)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
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