Lobeline HCl CAS 134-63-4
| CAS No. | 134-63-4 |
| Molecular Formula | C22H27NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Lobeline HCl (CAS 134-63-4), molecular formula C22H27NO2HCl and molecular weight 373.92 g/mol, is a CATO reference standard with documented purity and traceability.
Lobeline HCl (C22H27NO2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27NO2 HCl |
| Molecular Weight | 373.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lobeline Standards
- Lobeline impurity 20 (CAS 101113-68-2)
- Lobeline sulfate (CAS 134-64-5)
- Lobeline impurity 16 (CAS 2469224-15-3)
- Lobeline Impurity 2 (CAS 579-21-5)
- Lobeline impurity 14 (CAS 6168-88-3)
- Lobeline impurity 17 (CAS 775271-34-6（free base）)
- Lobeline Hydrochloride EP Impurity B (CAS CATO-C1893534)
- Lobeline Hydrochloride EP Impurity A (CAS CATO-C4X-18181)
Recommended Standards
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- 2-(2,3-Difluoro-6-methoxyphenyl)-1,3-dioxolane (CAS 773087-20-0)
- 4-Nitrophenyl α-L-Fucopyranoside (CAS 10231-84-2)
- 4-ethoxy-3-methoxyaniline (CAS 19782-77-5)
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- 4-(Trimethoxysilyl)aniline (CAS 33976-43-1)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
Why CATO?
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