Atorvastatin Calcium CAS 134523-03-8
| CAS No. | 134523-03-8 |
| Molecular Formula | 2*C33H34FN2O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Atorvastatin Calcium (CAS 134523-03-8), molecular formula C33H34FN2O5Ca and molecular weight 597.72 g/mol, is a CATO reference standard with documented purity and traceability.
Atorvastatin Calcium (C33H34FN2O5Ca) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Atorvastatin Calcium meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C33H34FN2O5 Ca |
| Molecular Weight | 597.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 22 (CAS 1035205-25-4)
- Atorvastatin Calcium Propylene Glycol Solvate (CAS 1040350-07-9)
- Atorvastatin Lactone Diepoxide (CAS 1046118-40-4)
- Atorvastatin Lactam calcium Salt Impurity (CAS 1046118-41-5)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Atorvastatin Impurity 76 (CAS 1099474-28-8)
- Atorvastatin EP Impurity F(Calcium Salt) (CAS 1105067-87-5)
Recommended Standards
- 6-Methyl-2,3-diphenyl-7,8-dihydroimidazo[1,2-b]pyridazine (CAS 89004-11-5)
- 2-(3,5-Dichloropyridin-2-yl)acetic acid (CAS 1000547-57-8)
- Ethyl 4-(2-(2-ethoxy-4-formyl-6-iodophenoxy)acetamido)benzoate (CAS 832677-97-1)
- Tert-butyl (3S,5S)-3,5-dihydroxypiperidine-1-carboxylate (CAS 2382089-24-7)
- (s)-2-Amino-2-(4-chloro-2-nitrophenyl)ethan-1-ol (CAS 1213640-74-4)
- Sodium 1,1,1-trifluoro-4-oxo-4-(pyridin-3-yl)but-2-en-2-olate (CAS 1006961-03-0)
- 5-(Benzylamino)-2-hydroxybenzoic acid (CAS 369640-15-3)
- 4-Methyl-5-(2-phenyl-1,3-thiazol-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 338760-15-9)
- 4-(4-(1H-Imidazol-1-yl)phenoxy)piperidine dihydrochloride (CAS 1187927-20-3)
- D-Trp25-Tirzepatide (CAS CATO-CPTD788909)
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