Atorvastatin EP Impurity F(Calcium Salt) CAS 1105067-87-5
| CAS No. | 1105067-87-5 |
| Molecular Formula | 2*C40H47FN3O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Atorvastatin EP Impurity F(Calcium Salt) is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 756.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Atorvastatin EP Impurity F(Calcium Salt) (CAS 1105067-87-5, C40H47FN3O8Ca) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C40H47FN3O8 Ca |
| Molecular Weight | 756.90 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Atorvastatin Standards
- Atorvastatin Impurity 22 (CAS 1035205-25-4)
- Atorvastatin Calcium Propylene Glycol Solvate (CAS 1040350-07-9)
- Atorvastatin Lactone Diepoxide (CAS 1046118-40-4)
- Atorvastatin Lactam calcium Salt Impurity (CAS 1046118-41-5)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Atorvastatin Impurity 76 (CAS 1099474-28-8)
- Atorvastatin EP Impurity E(Calcium salt) (CAS 1105067-88-6)
Recommended Standards
- Apixaban Impurity 14 (CAS 405872-78-8/2228998-99-8)
- Perindopril EP impurity M t-Butylamine (CAS CATO-C4X-125282)
- Ketotifen Impurity 27 (CAS CATO-C4X-204627)
- 2-(((4-Chloropyridin-2-yl)thio)methyl)benzonitrile (CAS 1346707-53-6)
- N-(3-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide (CAS 352330-53-1)
- 3-(2-Hydroxy-2-methylbenzo[d]oxazol-3(2H)-yl)propane-1-sulfonic acid (CAS 143413-71-2)
- Copper, [benzoic acid [(2-hydroxyphenyl)methylene]hydrazidato]chloro-, monohydrate (CAS 83614-45-3)
- Leflunomide Impurity 14 (CAS 51145-57-4)
- 2’,3’-Dideoxyadenosine 5’-Triphosphate (CAS 24027-80-3)
- Neuropeptide S (rat) (CAS 412938-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com