Cholic Acid Impurity 47 CAS 135013-44-4

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.135013-44-4
Molecular FormulaC28H48O4
Molecular Weight448.68 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cholic Acid Impurity 47 CAS 135013-44-4 chemical structure

Description

Cholic Acid Impurity 47 (CAS 135013-44-4) is a certified pharmaceutical impurity reference standard with the molecular formula C28H48O4 and a molecular weight of 448.68 g/mol.

The molecular framework of Cholic Acid Impurity 47 (C28H48O4) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Cholic Acid Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC28H48O4
Molecular Weight448.68 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995

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