Loperamide EP Impurity B Chloride CAS CATO-C4X-17882
| CAS No. | CATO-C4X-17882 |
| Molecular Formula | C47H53ClN3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Loperamide EP Impurity B Chloride (C47H53ClN3O3Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Loperamide EP Impurity B Chloride (CAS CATO-C4X-17882), a pharmacopoeial impurity reference standard (molecular formula C47H53ClN3O3Cl, MW 778.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loperamide EP Impurity B Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C47H53ClN3O3 Cl |
| Molecular Weight | 778.86 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loperamide Standards
- Loperamide EP Impurity F (CAS 106900-12-3)
- Loperamide EP Impurity G (CAS 109572-89-6)
- Loperamide EP Impurity G HCl (CAS 109572-89-6(free base))
- Loperamide EP Impurity D HCl (CAS 1134369-22-4)
- Loperamide impurity 14 (CAS 113817-55-3)
- Loperamide EP Impurity A (CAS 1391052-94-0)
- Loperamide EP Impurity E (CAS 1426322-82-8)
- Loperamide N-Oxide (CAS 217471-03-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com