2-(6-(Methylthio)-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethan-1-amine hydrochloride CAS 1351618-74-0
| CAS No. | 1351618-74-0 |
| Molecular Formula | C12H18N6S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(6-(Methylthio)-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethan-1-amine hydrochloride (CAS 1351618-74-0) is a high-purity analytical reference standard with the molecular formula C12H18N6SHCl and a molecular weight of 314.84 g/mol.
The molecular framework of 2-(6-(Methylthio)-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethan-1-amine hydrochloride (C12H18N6SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18N6S HCl |
| Molecular Weight | 314.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 4-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-6-ol (CAS 100047-41-4)
- 2-(Methylthio)-N-(2-(4-nitrophenoxy)ethyl)thiazolo[4,5-d]pyrimidin-7-amine (CAS 1000574-56-0)
- 4-Methyl-3-(methylthio)-7-nitro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1000575-87-0)
- 3-(Methylthio)-4-phenyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1000577-38-7)
- 5-Methyl-2-(methylthio)pyrimidine (CAS 100114-24-7)
- 6-benzyl-2-(methylthio)pyrimidin-4(3H)-one (CAS 100142-46-9)
- 2-(Methylthio)-5,6-dihydropyrimidin-4(1H)-one (CAS 100185-53-3)
- 4-(methylthio)-6-(tributylstannyl)pyrimidine (CAS 1002719-56-3)
Recommended Standards
- 2-(Oxolan-3-yloxy)ethan-1-amine (CAS 1274539-59-1)
- 3-(4-methoxyphenyl)butan-2-one (CAS 7074-12-6)
- 1-[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrrolidine-2,5-dione (CAS 2096997-21-4)
- 3,4-Difluoro-2-methylbenzophenone (CAS 746651-91-2)
- Tamsulosin EP Impurity F (CAS 6781-17-5)
- N-Nitroso-Cyclamate (CAS 70365-40-1)
- (2,3-Dichlorobenzyl)glycine (CAS 1094404-11-1)
- Ethyl 5-amino-4-bromo-1-cyclohexyl-1H-pyrazole-3-carboxylate (CAS 1427021-84-8)
- (5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanamine (CAS 944897-68-1)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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