6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one CAS 1354745-52-0
| CAS No. | 1354745-52-0 |
| Molecular Formula | C24H17ClF3NO4 |
| Molecular Weight | 475.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one.
6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one (CAS 1354745-52-0) is a high-purity analytical reference standard with the molecular formula C24H17ClF3NO4 and a molecular weight of 475.84 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 475.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H17ClF3NO4 |
| Molecular Weight | 475.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (2Z)-2-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one 1025277-30-8 MS-9216 (CAS 1025277-30-8)
- 3-(2-Chloro-6-fluorophenyl)-5-methyl-N-{3-[5-(trifluoromethyl)pyridin-2-yl]phenyl}-1,2-oxazole-4-carboxamide (CAS 1092346-37-6)
- N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyridin-3-yl)-4-methylbenzamide (CAS 478262-12-3)
- N-[4-chloro-3-(trifluoromethyl)phenyl]-N-(phenylsulfonyl)benzenesulfonamide (CAS 854035-98-6)
- (6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1,2:1,5]pyrrolo[2,3-d]pyridazine-4-carboxam (CAS 870005-19-9)
- 3-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-1-[3-(trifluoromethyl)phenyl]urea (CAS 477864-65-6)
- 3-Chloro-2-({7-[(Z)-2-[4-(propan-2-yl)phenyl]ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}sulfanyl)-5-(trifluoromethyl)pyridine (CAS 303986-70-1)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-57-9)
Recommended Standards
- Diphenyl ((1H-benzo[d][1,2,3]triazol-1-yl)(4-chlorophenyl)methyl)phosphonate (CAS 676562-43-9)
- (4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-1H-purin-8-yl)phenyl)phosphonic acid (CAS 1373822-39-9)
- Dotinurad Impurity 95 (CAS CATO-C4X-249495)
- 5-((4-Chlorophenyl)thio)-4-((2,6-dichlorophenoxy)methyl)-1-methyl-3-phenyl-1H-pyrazole (CAS 318248-34-9)
- 1-[1-(4-Ethylphenyl)-1H-1,2,3-triazole-4-carbonyl]piperidin-4-amine (CAS 1351779-88-8)
- (3-(2-Chlorophenyl)isoxazol-5-yl)methanamine (CAS 543713-32-2)
- Phenyl Trifluoroacetate (CAS 500-73-2)
- Methyl 7-fluoro-3-oxo-3,4-dihydroquinoxaline-2-carboxylate (CAS 221167-39-1)
- 1-Nitronaphthalen-2-ol (CAS 550-60-7)
- 2-(6-Chloropyridin-3-yl)-5-methylthiazol-4-yl thiophene-2-carboxylate (CAS 400081-00-7)
- N-ethyl-N-methylpyrrolidin-3-amine dihydrochloride (CAS 1803607-79-5)
- di-tert-Butyl 2,2'-(Cyclopropane-1,1-diyl)(4S,4'S)-bis(4,5-dihydrooxazole-4-carboxylate) (CAS 2328084-27-9)
- 90E3PV880Q 7790-75-2 Calcium tungstate Calcium tungstate(VI) Calcium tungsten oxide (CaWO4) Calcium wolframate, of a kind used as a luminophore Tungstate (WO42-), calcium (1:1), (beta-4)- Tungstic acid (H2WO4) calcium salt (1:1) EINECS 232-219-4 UNII-90E3PV880Q (CAS 7790-75-2)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com