N-[4-chloro-3-(trifluoromethyl)phenyl]-N-(phenylsulfonyl)benzenesulfonamide CAS 854035-98-6
| CAS No. | 854035-98-6 |
| Molecular Formula | C19H13ClF3NO4S2 |
| Molecular Weight | 475.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-[4-chloro-3-(trifluoromethyl)phenyl]-N-(phenylsulfonyl)benzenesulfonamide (CAS 854035-98-6), molecular formula C19H13ClF3NO4S2 and molecular weight 475.89 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-[4-chloro-3-(trifluoromethyl)phenyl]-N-(phenylsulfonyl)benzenesulfonamide (C19H13ClF3NO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-[4-chloro-3-(trifluoromethyl)phenyl]-N-(phenylsulfonyl)benzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H13ClF3NO4S2 |
| Molecular Weight | 475.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related N Standards
- N-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)pyridin-3-yl)-4-methylbenzamide (CAS 478262-12-3)
- (6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-N,8-diethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-6-methyl-1,9-dioxo-pyrazino[1,2:1,5]pyrrolo[2,3-d]pyridazine-4-carboxam (CAS 870005-19-9)
- 3-Chloro-2-({7-[(Z)-2-[4-(propan-2-yl)phenyl]ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}sulfanyl)-5-(trifluoromethyl)pyridine (CAS 303986-70-1)
- (2Z)-2-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one 1025277-30-8 MS-9216 (CAS 1025277-30-8)
- 6-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one (CAS 1354745-52-0)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-57-9)
- 3-(2-Chloro-6-fluorophenyl)-5-methyl-N-{3-[5-(trifluoromethyl)pyridin-2-yl]phenyl}-1,2-oxazole-4-carboxamide (CAS 1092346-37-6)
- 2-Chloro-1-[1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydro-2(1H)-isoquinolinyl]ethanone (CAS 730949-62-9)
Recommended Standards
- 4-[6-(4-Methyl-piperazin-1-yl)-5-trifluoromethyl-pyridin-3-yl]-benzoic acid 4-chloro-phenyl ester (CAS 1311279-90-9)
- Methyl 2-[bis(2,2,2-trifluoroethoxy)phosphoryl]-2,2-dibromo-acetate (CAS 318967-86-1)
- Metazosulfuron (CAS 868680-84-6)
- Lapatinib Impurity 19 (CAS 320337-48-2)
- 1,3-Benzothiazole-7-carbonitrile (CAS 895525-11-8)
- 4-Amino-n-isopropyl-n,2-dimethylbenzenesulfonamide (CAS 1095035-67-8)
- 7-Oxabicyclo[2.2.1]heptane-2-carbothioamide (CAS 1343132-85-3)
- Benzene, 1-bromo-3-(bromomethyl)-2-iodo- (CAS 1261757-20-3)
- 4-chloro-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 870706-47-1)
- N,4-dimethyl-5-(1-propylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352539-10-6)
- 5-Amino-1-(thiophen-2-ylmethyl)pyrimidine-2,4(1h,3h)-dione (CAS 1341598-54-6)
- 8LTE57JMN4 151466-23-8 Imidazo(4,5-d)pyrano(4,3-b)pyridine, 1,6,7,9-tetrahydro-2-(3-isoxazolyl)-,phosphate (1:1) UNII-8LTE57JMN4 S-8510 (CAS 151466-23-8)
- 2-Bromo-5-cyano-3-(trifluoromethyl)benzenesulfonyl chloride (CAS 1805416-70-9)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com