Mometasone Furoate EP Impurity E CAS 1370190-33-2
| CAS No. | 1370190-33-2 |
| Molecular Formula | C32H32Cl2O8 |
| Molecular Weight | 615.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 615.50 g/mol gives Mometasone Furoate EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Mometasone Furoate EP Impurity E (CAS 1370190-33-2) is a certified pharmaceutical impurity reference standard with the molecular formula C32H32Cl2O8 and a molecular weight of 615.50 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Mometasone Furoate EP Impurity E is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 615.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H32Cl2O8 |
| Molecular Weight | 615.50 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Impurity 44 (CAS CATO-C4X-170444)
- Mometasone Impurity 45 (CAS 424787-89-3)
- Mometasone Furoate EP Impurity I (CAS CATO-C4X-170410)
- Mometasone Furoate EP Impurity R (CAS 1370190-08-1)
- Mometasone Impurity 43 (CAS CATO-C4X-170443)
- Mometasone Impurity 32 (CAS CATO-C4X-170432)
- Mometasone Impurity 46 (CAS CATO-C4X-170446)
- Mometasone Furoate EP Impurity B (CAS 223776-49-6)
Recommended Standards
- Dacomitinib Impurity 19 (CAS CATO-C4X-208619)
- Lifitegrast Impurity 14 (CAS CATO-C4X-240914)
- Azido-PEG8-TFP ester (CAS 1818294-49-3)
- Lifitegrast Impurity 102 (CAS CATO-C4X-2409102)
- Thioctic acid Impurity 25 (CAS 728854-75-9)
- Isavuconazole Impurity 223 (CAS CATO-C4X-1236223)
- Lenvatinib Impurity 110 (CAS CATO-C4X-1140110)
- 3-Thiophenecarboxylic acid, 5-(1-methylethyl)-, hydrazide (9CI) 438221-49-9 (CAS 438221-49-9)
- Benzyl 4-(((2-aminoethyl)(ethyl)amino)methyl)piperidine-1-carboxylate (CAS 1353972-73-2)
- (S)-4-((1,4,7,10-Tetrakis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-2-yl)methyl)benzoic acid (CAS 1713269-98-7)
- 3-Iodo-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid (CAS 1190311-30-8)
- 1-(Quinazolin-6-yl)ethanone (CAS 851444-87-6)
- Ethyl 5-(4-chloro-2-fluorophenoxy)pentanoate (CAS 1443333-88-7)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com