Mometasone Impurity 46 CAS CATO-C4X-170446
| CAS No. | CATO-C4X-170446 |
| Molecular Formula | C34H37ClO9S |
| Molecular Weight | 657.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Mometasone Impurity 46 (CAS CATO-C4X-170446, C34H37ClO9S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Mometasone Impurity 46 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 657.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C34H37ClO9S |
| Molecular Weight | 657.17 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Mometasone Standards
- Mometasone Impurity 45 (CAS 424787-89-3)
- Mometasone Impurity 44 (CAS CATO-C4X-170444)
- Mometasone Furoate EP Impurity E (CAS 1370190-33-2)
- Mometasone Furoate EP Impurity I (CAS CATO-C4X-170410)
- Mometasone Furoate EP Impurity R (CAS 1370190-08-1)
- Mometasone Impurity 43 (CAS CATO-C4X-170443)
- Mometasone Impurity 32 (CAS CATO-C4X-170432)
- Mometasone Furoate EP Impurity B (CAS 223776-49-6)
Recommended Standards
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