Rimegepant Impurity 70 CAS 1373116-04-1
| CAS No. | 1373116-04-1 |
| Molecular Formula | C25H36F2N2OSi |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Rimegepant Impurity 70 (C25H36F2N2OSiHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Rimegepant Impurity 70 (CAS 1373116-04-1) is a certified pharmaceutical impurity reference standard with the molecular formula C25H36F2N2OSiHCl and a molecular weight of 483.12 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H36F2N2OSi HCl |
| Molecular Weight | 483.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Rimegepant Standards
- Rimegepant Impurity 63 (CAS 1071154-76-1)
- Rimegepant Impurity 102 (CAS 1146515-11-8)
- Rimegepant Impurity 61 (CAS 1190363-43-9)
- Rimegepant Impurity 9 (CAS 1190363-46-2)
- Rimegepant Impurity 59 (CAS 1190363-47-3)
- Rimegepant Impurity 17 (CAS 1190363-50-8)
- Rimegepant (CAS 1289023-67-1)
- Rimegepant Impurity 51 (CAS 1289023-89-7)
Recommended Standards
- Linezolid Impurity 62 (CAS 16483-45-7)
- N-Nitroso Risperidone Impurity 48 (CAS CATO-C4X-111148)
- Pregabalin Impurity PD0310887 (CAS CATO-C4X-131210)
- Diethyl 5-(hydroxymethyl)isophthalate (CAS 181425-91-2)
- Carbetocin Impurity 37 (CAS CATO-C4X-191137)
- Sitagliptin-d4 Phosphate (CAS 1432063-88-1)
- Silodosin-d4 (CAS 1426173-86-5)
- 4-(Triethoxymethyl)pyridine (CAS 1033750-30-9)
- 2-(Methylamino)-[1,2,4]thiadiazolo[2,3-a]pyridin-4-ium chloride (CAS 188830-69-5)
- Peptide 439 (CAS CATO-CPTD788439)
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