Olopatadine Impurity 35 CAS 1376615-97-2
| CAS No. | 1376615-97-2 |
| Molecular Formula | C21H23NO2 |
| Molecular Weight | 321.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Olopatadine Impurity 35 (CAS 1376615-97-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23NO2 and a molecular weight of 321.41 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Olopatadine Impurity 35 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 321.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23NO2 |
| Molecular Weight | 321.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Olopatadine Standards
- Olopatadine impurity 146 (CAS CATO-C4X-1135146)
- Olopatadine Impurity 9 (CAS 113835-92-0)
- Olopatadine Impurity N3 (CAS 113835-76-0)
- Olopatadine Impurity 19 (CAS 55690-15-8)
- Olopatadine Impurity 11 (CAS 56427-76-0)
- Olopatadine Carbaldehyde (CAS CATO-C4X-171815)
- Olopatadine lmpurity 61 (CAS CATO-C4X-171862)
- Olopatadine Impurity 47 (CAS 872040-99-8)
Recommended Standards
- Gabapentin Impurity 26 (CAS CATO-C4X-165426)
- Brivaracetam Impurity 214 (CAS CATO-C4X-2007214)
- Gabapentin Impurity 20 (CAS CATO-C4X-165420)
- Levalbuterol Impurity 3 (CAS CATO-C4X-22593)
- Clofarabine Impurity 16 (CAS CATO-C4X-159316)
- Sodium aminosalicylate EP Impurity A(Mesalazine EP Impurity B) (CAS 591-27-5)
- Cyclophosphamide EP Impurity C HCl (CAS 821-48-7)
- 2,2-Dichloro-N,N-diethylacetamide (CAS 921-88-0)
- 5-(Methoxymethyl)-1,2-dihydro-3H-1,2,4-triazole-3-thione (CAS 78201-12-4)
- Baricitinib Impurity 110 (CAS CATO-C4X-2260110)
- 1-(Quinolin-2-yl)piperidine-4-carboxylic acid hydrochloride (CAS 1354953-67-5)
- 1-((2-Carbamothioylhydrazono)methyl)isoquinoline-5-sulfonic acid (CAS 20335-55-1)
- 4-Azetidinomethyl-4-cyanobenzophenone (CAS 898777-49-6)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com