Diphenhydramine N-Glucuronide CAS 137908-78-2
| CAS No. | 137908-78-2 |
| Molecular Formula | C23H29NO7 |
| Molecular Weight | 431.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 431.48 g/mol gives Diphenhydramine N-Glucuronide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Diphenhydramine N-Glucuronide (CAS 137908-78-2), molecular formula C23H29NO7 and molecular weight 431.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Diphenhydramine N-Glucuronide (C23H29NO7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29NO7 |
| Molecular Weight | 431.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 1 |
Related Diphenhydramine Standards
- Diphenhydramine impurity 16 (CAS CATO-C4X-142416)
- Diphenhydramine EP Impurity C (CAS 118-23-0)
- Diphenhydramine impurity 18 (CAS 150556-79-9)
- Diphenhydramine impurity 17 (CAS 22808-17-9)
- Diphenhydramine impurity 9 (CAS CATO-C4X-14249)
- Diphenhydramine impurity 14 (CAS CATO-C4X-142414)
- Diphenhydramine N-Oxide (CAS 3922-74-5)
- Diphenhydramine EP Impurity B (CAS 19804-27-4)
Recommended Standards
- Fmoc-S-3-amino-4-(4-methoxyphenyl)-butyric acid (CAS 1352435-52-9)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-methoxy-4-methylphenyl)propanoic acid (CAS 1379865-86-7)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)butanoic acid (CAS 1313054-84-0)
- 4-Benzyl-3-(2-(3-(benzyloxy)-4-methoxyphenyl)acetyl)oxazolidin-2-one (CAS 141733-91-7)
- 2-(Piperidin-4-yl)aniline (CAS 255050-94-3)
- 2-Fluoro-6-iodo-3-(trifluoromethyl)benzoic acid (CAS 1055176-29-8)
- 2-Amino-5-(2-methylpropyl)-1,3-oxazole-4-carboxylic acid (CAS 1820735-48-5)
- 2-Cyclopropoxy-6-iodo-N-methylaniline (CAS 1243376-50-2)
- Diethyl 4-aminoisothiazole-3,5-dicarboxylate (CAS 72632-87-2)
- Pyrazolo[1,5-b]pyridazine-3-carboxylic Acid (CAS 88561-91-5)
- 5-(3-(Trifluoromethyl)benzyl)-1,3,4-thiadiazol-2-amine (CAS 57552-39-3)
- 3-Hydroxy-5-(methylamino)benzoic Acid (CAS 89611-00-7)
- 5-Bromosalicylaldehyde (CAS 1761-61-1)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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