Clopidogrel Impurity 16 CAS 138228-61-2
| CAS No. | 138228-61-2 |
| Molecular Formula | C8H9ClN2O |
| Molecular Weight | 184.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Clopidogrel Impurity 16 (CAS 138228-61-2), a pharmacopoeial impurity reference standard (molecular formula C8H9ClN2O, MW 184.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Clopidogrel Impurity 16 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Clopidogrel Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2O |
| Molecular Weight | 184.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clopidogrel Standards
- Clopidogrel Impurity 87 (CAS 26118-14-9)
- Clopidogrel Impurity 12 (CAS 141196-64-7)
- Clopidogrel Impurity 67 (CAS 7292-71-9)
- Clopidogrel Impurity 68 (CAS 6212-33-5)
- Clopidogrel Impurity 69 (CAS 131202-62-5)
- Clopidogrel Impurity 88 (CAS 34966-49-9)
- Clopidogrel Impurity 98 (CAS 76103-96-3)
- Clopidogrel Impurity 5 (CAS 141109-16-2)
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- 5-(5-aminopentylamino)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione (CAS 2307476-95-3)
- 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-3-nitrovalerophenone (CAS 898786-33-9)
- Methyl 7-chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carboxylate (CAS 577691-69-1)
- (1R,3S,5S)-rel-Bicyclo[3.1.0]hexan-3-ol (CAS 694-44-0)
- tert-Butyl N-[trans-6-methylpiperidin-3-yl]carbamate (CAS 1222491-53-3)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com