Clopidogrel Impurity 67 CAS 7292-71-9
| CAS No. | 7292-71-9 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Clopidogrel Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Clopidogrel Impurity 67 (CAS 7292-71-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol.
Clopidogrel Impurity 67 (C8H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clopidogrel Standards
- Clopidogrel Impurity 12 (CAS 141196-64-7)
- Clopidogrel Impurity 68 (CAS 6212-33-5)
- Clopidogrel Impurity 16 (CAS 138228-61-2)
- Clopidogrel Impurity 87 (CAS 26118-14-9)
- Clopidogrel Impurity 88 (CAS 34966-49-9)
- Clopidogrel Impurity 98 (CAS 76103-96-3)
- Clopidogrel Impurity 69 (CAS 131202-62-5)
- Clopidogrel Impurity 5 (CAS 141109-16-2)
Recommended Standards
- 2-amino-2-(4-chlorophenyl)acetic acid 7292-70-8 (CAS 7292-70-8)
- Paracetamol EP Impurity C (CAS 3964-54-3)
- NSC 289800 (CAS 66999-51-7)
- Nintedanib Impurity 67 (CAS 40872-87-5)
- Ramipril EP Impurity M (CAS 2743-38-6)
- Azilsartan Impurity 60 (CAS CATO-C4X-109660)
- Paroxetine Impurity 81 (CAS 2945089-65-4)
- 4-(Trifluoromethyl)benzoic anhydride (CAS 25753-16-6)
- N-(2,4-dichloro-5-isopropoxyphenyl)-4,5-dihydrothiazol-2-amine (CAS 400736-23-4)
- 1-(1-(1-(Methylsulfonyl)-1H-pyrazol-3-yl)ethyl)-1H-1,2,4-triazole (CAS 400077-64-7)
- N-(4-Aminophenyl)ethenesulfonamide (CAS 37862-57-0)
- tert-Butyl (2-bromo-4-nitrophenyl)carbamate (CAS 384793-20-8)
- 7-Methoxy-4-methyl-1,2,3,4-tetrahydroquinoline (CAS 179899-10-6)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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