Apremilast impurity 15 CAS 1384441-38-6
| CAS No. | 1384441-38-6 |
| Molecular Formula | C21H22N2O7S |
| Molecular Weight | 446.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Apremilast impurity 15.
CATO supplies Apremilast impurity 15 (CAS 1384441-38-6), a pharmacopoeial impurity reference standard (molecular formula C21H22N2O7S, MW 446.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Apremilast impurity 15 (C21H22N2O7S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apremilast impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H22N2O7S |
| Molecular Weight | 446.47 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 23 (CAS 2077897-94-8)
- Apremilast Impurity 45 (CAS CATO-C4X-100945)
- Apremilast Impurity 75 (CAS CATO-C4X-100975)
- Apremilast impurity 8 (CAS CATO-C4X-10098)
- Apremilast Impurity 36 (CAS 253168-82-0)
- Apremilast Impurity 38 (CAS 2095036-40-9)
- Apremilast Impurity 52 (CAS CATO-C4X-100952)
- Apremilast Impurity 78 (CAS CATO-C4X-100978)
Recommended Standards
- Tris(4-(4H-1,2,4-triazol-4-yl)phenyl)amine (CAS 2001066-82-4)
- NFAT Inhibitor-2 (CAS 422546-87-0)
- Ethyl3,6-dioxo-2-(triphenylphosphoranylidene)heptanoate (CAS 62251-87-0)
- 7-(4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl)-2-methyl-3-(3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 865658-68-0)
- Thioctic acid Impurity 27 (CAS 2114407-82-6)
- Arbidol Impurity 47 (CAS 85237-86-1)
- Ozanimod Impurity 29 (CAS CATO-C4X-290229)
- 2-(Difluoromethoxy)benzothioamide (CAS 1094293-72-7)
- Methyl quinoline-8-carbodithioate (CAS 112307-45-6)
- 1,3-Dibromo-5,7-bis(2-ethylhexyl)-4H,8H-benzo[1,2-c:4,5-c']dithiophene-4,8-dione (CAS 1415929-76-8)
- 2-Methoxy-3,4,5-triphenylfuran (CAS 31554-21-9)
- 5-Nitroquinoline 1-Oxide (CAS 7613-19-6)
- Ezetimibe Impurity 1 (CAS 204589-58-2)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com