Apremilast Impurity 75 CAS CATO-C4X-100975
| CAS No. | CATO-C4X-100975 |
| Molecular Formula | C21H22N2O7S |
| Molecular Weight | 446.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Apremilast Impurity 75 (CAS CATO-C4X-100975) is a certified pharmaceutical impurity reference standard with the molecular formula C21H22N2O7S and a molecular weight of 446.47 g/mol.
Based on its molecular formula C21H22N2O7S, Apremilast Impurity 75 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 446.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22N2O7S |
| Molecular Weight | 446.47 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast impurity 15 (CAS 1384441-38-6)
- Apremilast Impurity 23 (CAS 2077897-94-8)
- Apremilast Impurity 45 (CAS CATO-C4X-100945)
- Apremilast impurity 8 (CAS CATO-C4X-10098)
- Apremilast Impurity 36 (CAS 253168-82-0)
- Apremilast Impurity 38 (CAS 2095036-40-9)
- Apremilast Impurity 52 (CAS CATO-C4X-100952)
- Apremilast Impurity 78 (CAS CATO-C4X-100978)
Recommended Standards
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- 4-Fluoro-3-(piperazin-1-yl)aniline (CAS 105377-03-5)
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