Phenylephrine Impurity 9 CAS 1391194-66-3
| CAS No. | 1391194-66-3 |
| Molecular Formula | C9H12BrNO2 |
| Molecular Weight | 246.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Phenylephrine Impurity 9 (C9H12BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Phenylephrine Impurity 9 (CAS 1391194-66-3), a pharmacopoeial impurity reference standard (molecular formula C9H12BrNO2, MW 246.10 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12BrNO2 |
| Molecular Weight | 246.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Phenylephrine Standards
- Phenylephrine Impurity 10 (CAS 1391194-63-0)
- Phenylephrine Impurity 11 (CAS 1391194-51-6)
- Phenylephrine Impurity 52 (CAS 1785420-81-6)
- Phenylephrine-3-O-Sulfate (CAS 1242184-39-9)
- Phenylephrine Impurity 8 (CAS CATO-C4X-14678)
- Phenylephrine Impurity 90 (CAS CATO-C4X-146790)
- Phenylephrine Impurity 103 (CAS CATO-C4X-1467103)
- Phenylephrine impurity 94 (CAS 83070-12-6)
Recommended Standards
- Pinaverium impurity 25 (CAS 89525-51-9)
- Moxonidine EP Impurity A (CAS 352457-35-3)
- 2-Bromocarbazole (CAS 3652-90-2)
- WDG35UDX67 5332-26-3 N-(Bromomethyl)phthalimide 1H-Isoindole-1,3(2H)-dione, 2-(bromomethyl)- AI3-28934 EINECS 226-239-2 NSC 3997 Phthalimide, N-(bromomethyl)- Phthalimidomethyl bromide UNII-WDG35UDX67 (CAS 5332-26-3)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
- Lornoxicam impurity 62 (CAS CATO-C4X-201662)
- Mirogabalin Impurity 125 (CAS 1415817-34-3)
- N-(6-Hydroxy-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 824429-50-7)
- (E)-Oct-2-en-1-yl acetate (CAS 3913-80-2)
- 3-Methoxy-N,5-dimethylaniline (CAS 35122-78-2)
- 4-Methoxy-6-(methylselanyl)pyrimidin-2-amine (CAS 100559-66-8)
- Aztreonam tert butyl ester (CAS 330944-50-8)
- 2-Bromo-5-(trifluoromethoxy)benzaldehyde (CAS 505084-61-7)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com