Ivacaftor-d9 CAS 1413431-07-8
| CAS No. | 1413431-07-8 |
| Molecular Formula | - |
| Molecular Weight | 401.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ivacaftor-d9 (CAS 1413431-07-8) is a high-purity analytical reference standard with the molecular formula C24H19D9N2O3 and a molecular weight of 401.55 g/mol.
Ivacaftor-d9 (C24H19D9N2O3) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ivacaftor-d9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H19D9N2O3 |
| Molecular Weight | 401.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Ivacaftor Standards
- Ivacaftor Carboxylic Acid Lactone (CAS 1246213-41-1)
- Ivacaftor-d4 (CAS CATO-C4X-296421)
- Ivacaftor-d18 (CAS 1413431-05-6)
- Ivacaftor Impurity 15 (CAS 2760759-58-6)
- Ivacaftor Impurity 5 (CAS 873051-52-6)
- Ivacaftor (CAS 873054-44-5)
- Ivacaftor impurity 16 (CAS CATO-C4X-296416)
- Ivacaftor impurity 19 (CAS CATO-C4X-296419)
Recommended Standards
- 2-((3-(sec-Butyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-(3,5-dimethylphenyl)acetamide (CAS 1326865-62-6)
- N-(1-(4-(Ethylsulfonyl)phenyl)piperidin-4-yl)benzo[d]thiazol-2-amine (CAS 1444303-39-2)
- N-(4-Butylphenyl)-2-((3-ethyl-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1252904-00-9)
- 2-Oxoethyl (4-(((R)-3-aminobutyl)amino)-2-((6-guanidinohexyl)amino)butyl)carbamate (CAS 170368-04-4)
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