Ivacaftor impurity 16 CAS CATO-C4X-296416
| CAS No. | CATO-C4X-296416 |
| Molecular Formula | C24H27N3O4 |
| Molecular Weight | 421.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Ivacaftor impurity 16 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 421.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ivacaftor impurity 16 (CAS CATO-C4X-296416), a pharmacopoeial impurity reference standard (molecular formula C24H27N3O4, MW 421.49 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ivacaftor impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H27N3O4 |
| Molecular Weight | 421.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Ivacaftor Standards
- Ivacaftor impurity 19 (CAS CATO-C4X-296419)
- Ivacaftor Impurity 20 (CAS CATO-C4X-296420)
- Ivacaftor Carboxylic Acid (CAS 1246213-24-0)
- Ivacaftor Carboxylic Acid Lactone (CAS 1246213-41-1)
- Ivacaftor-d9 (CAS 1413431-07-8)
- Ivacaftor-d4 (CAS CATO-C4X-296421)
- Ivacaftor-d18 (CAS 1413431-05-6)
- Ivacaftor Impurity 15 (CAS 2760759-58-6)
Recommended Standards
- Finerenone Impurity 209 (CAS CATO-C4X-2880209)
- Daprodustat impurity 27 (CAS 960540-96-9)
- LCZ-696 Impurity 86 (CAS 1795787-14-2)
- (E)-Fenpyroximate (CAS 134098-61-6)
- Ketoprofen Impurity 115 (CAS 72235-46-2)
- Encorafenib Impurity 2 (CAS 1269440-29-0)
- Ibuprofen Impurity 73 (CAS 75625-99-9)
- (<I>RS</I>)-(Methylenecyclopropyl)acetic acid (CAS 1073-00-3)
- 3-Amino-2-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227587-09-8)
- (2S,3S)-2-(2-Ethoxyphenyl)-1-(2-methoxyethyl)-6-oxopiperidine-3-carboxylic acid (CAS 1391479-07-4)
- 4-(1-Cyanocyclopropyl)-3-fluorophenylboronic acid (CAS 2377611-05-5)
- o-Toluidine-4,6-d2 (CAS 68408-20-8)
- 3-Hydroxy-4-methoxypicolinonitrile (CAS 1026681-06-0)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com