Avibactam Impurity 55 CAS 1416134-74-1
| CAS No. | 1416134-74-1 |
| Molecular Formula | C14H20N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Avibactam Impurity 55 (C14H20N2O3C2H2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Avibactam Impurity 55 (CAS 1416134-74-1, C14H20N2O3C2H2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avibactam Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H20N2O3 C2H2O4 |
| Molecular Weight | 354.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Avibactam Standards
- Avibactam Impurity 133 (CAS 1133931-73-3)
- Avibactam impurity 113 (CAS 115134-37-7)
- Avibactam Impurity 89 (CAS 1171080-45-7)
- Avibactam Impurity 22 (CAS 1174020-25-7)
- Avibactam Sodium Salt (CAS 1192491-61-4)
- Avibactam-13C5,15N Sodium Salt (CAS 1192491-61-4 (non-labelled))
- Avibactam Impurity 02 (CAS 1192500-31-4)
- Avibactam Impurity 56（2S,5R) (CAS 1192651-49-2)
Recommended Standards
- Azilsartan Impurity 74 (CAS 139481-33-7)
- Macitentan Impurity 13 (CAS 2089065-77-8)
- Peramivir Impurity 74 (CAS CATO-C4X-183374)
- 2-(5-(Thiophen-2-yl)isoxazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide (CAS 946227-83-4)
- 5,8-Dihydroxy-2-(hydroxymethyl)quinazolin-4(1H)-one (CAS 117498-07-4)
- 3-Chloro-4-methoxy-N-propylaniline (CAS 99177-60-3)
- 4-(Difluoromethylene)cyclohexan-1-amine (CAS 2253632-70-9)
- 2-(3-Methoxyphenyl)-N-(2-methylpyrazolo[1,5-a]pyrimidin-6-yl)acetamide (CAS 1797978-17-6)
- 1,1-Diphenyl-3-(p-tolyl)isoquinolin-4(1H)-one (CAS 102301-79-1)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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