Cabazitaxel Impurity 4 CAS 1420767-25-4
| CAS No. | 1420767-25-4 |
| Molecular Formula | C44H55NO14 |
| Molecular Weight | 821.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabazitaxel Impurity 4.
Cabazitaxel Impurity 4 (CAS 1420767-25-4) is a certified pharmaceutical impurity reference standard with the molecular formula C44H55NO14 and a molecular weight of 821.91 g/mol.
Cabazitaxel Impurity 4 (C44H55NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cabazitaxel Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C44H55NO14 |
| Molecular Weight | 821.91 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Cabazitaxel Standards
- Cabazitaxel Impurity 10 (CAS CATO-C4X-111510)
- Cabazitaxel Impurity 2 (CAS 160084-81-1)
- Cabazitaxel Impurity 14 (CAS CATO-C4X-111514)
- Cabazitaxel (CAS 183133-96-2)
- Cabazitaxel Impurity 16 (CAS CATO-C4X-111516)
- Cabazitaxel Impurity 18 (CAS 1714967-27-7)
- Cabazitaxel Impurity 35 (CAS CATO-C4X-111535)
- Cabazitaxel Impurity 36 (CAS CATO-C4X-111536)
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