Roxadustat Impurity N3 CAS 1421312-34-6
| CAS No. | 1421312-34-6 |
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Roxadustat Impurity N3 (CAS 1421312-34-6, C18H15NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Roxadustat Impurity N3 (C18H15NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 309.32 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Roxadustat Impurity N3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15NO4 |
| Molecular Weight | 309.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity N1 (CAS 808116-52-1)
- Roxadustat Impurity 39 (CAS CATO-C4X-221339)
- Roxadustat Impurity 73 (CAS CATO-C4X-221373)
- Roxadustat Impurity 48 (CAS CATO-C4X-221348)
- Roxadustat Impurity 165 (CAS CATO-C4X-2213165)
- Roxadustat Impurity 89 (CAS CATO-C4X-221389)
- Roxadustat Impurity 92 (CAS CATO-C4X-221392)
- Roxadustat Impurity N6 (CAS 1421312-32-4)
Recommended Standards
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- H-Gly-Ala-Tyr-OH (CAS 92327-84-9)
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- H-Tyr-Gln-OH (CAS 28252-40-6)
- Cenobamate Impurity 49 (CAS CATO-C4X-241649)
- Citalopram Impurity 38 (CAS 103146-26-5)
- Teduglutide Impurity 2 (CAS CATO-C4X-23642)
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- 5-Iodo-3-methylisothiazole-4-carboxylic acid (CAS 1383546-18-6)
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- 1-(4-Acetylphenyl)-5-methyl-2,3-dihydro-1h-imidazol-2-one (CAS 14059-26-8)
- 4-(2-(Piperidin-1-yl)ethoxy)benzoyl chloride (CAS 166975-76-4)
- Angiotensin III Antipeptide (CAS 133605-55-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com