Alogliptin Impurity 46 CAS 1430222-06-2
| CAS No. | 1430222-06-2 |
| Molecular Formula | C14H12ClN3O2 |
| Molecular Weight | 289.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Alogliptin Impurity 46 (CAS 1430222-06-2) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12ClN3O2 and a molecular weight of 289.72 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Alogliptin Impurity 46 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 289.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Alogliptin Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12ClN3O2 |
| Molecular Weight | 289.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Alogliptin Standards
- Alogliptin Impurity 56 (CAS 454713-13-4)
- Alogliptin Impurity 64 (CAS 1485536-93-3)
- Alogliptin Impurity 100 (CAS CATO-C4X-1099100)
- Alogliptin Impurity 50 (CAS 1883825-48-6)
- Alogliptin Impurity 67 (CAS 865759-24-6)
- Alogliptin Impurity 44-d3 (CAS 1794937-18-0)
- Alogliptin Impurity 17 (CAS 865758-96-9)
- Alogliptin Impurity 27 (CAS CATO-C4X-109927)
Recommended Standards
- N-allyl-4-chloro-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxamide (CAS 339031-69-5)
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- N-[3-Chloro-4-(pyrimidin-2-yloxy)phenyl]cyclopropanecarboxamide (CAS 338413-34-6)
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- Lasmiditan Impurity 75 (CAS CATO-C4X-247875)
- Atracurium Impurity 41 (CAS CATO-C4X-185041)
- Haloperidol Impurity 10 (CAS 100442-88-4)
- Deuteroporphyrin IX 2-vinyl, 4-hydroxymethyl (CAS 141407-08-1)
- 2,6,7-Trimethylquinolin-4-ol (CAS 948291-42-7)
- 5-Bromo-4-chloro-6-methoxypyrimidin-2-amine (CAS 1158074-71-5)
- 4-(2-Bromophenylamino)-1,1,1-trifluorobut-3-en-2-one (CAS 176722-52-4)
- 2-Iodothiazole-4-carbonitrile (CAS 1261562-55-3)
- 2-(chloromethyl)-5-ethoxypyridine hydrochloride (CAS 133238-81-0)
- Semaglutide Impurity 121 X Sodium Salt (CAS CATO-C4X-2226121)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com