Alogliptin Impurity 67 CAS 865759-24-6
| CAS No. | 865759-24-6 |
| Molecular Formula | C13H11ClFN3O2 |
| Molecular Weight | 295.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 295.70 g/mol gives Alogliptin Impurity 67 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Alogliptin Impurity 67 (CAS 865759-24-6), a pharmacopoeial impurity reference standard (molecular formula C13H11ClFN3O2, MW 295.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Alogliptin Impurity 67 (C13H11ClFN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alogliptin Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11ClFN3O2 |
| Molecular Weight | 295.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Alogliptin Standards
- Alogliptin Impurity 100 (CAS CATO-C4X-1099100)
- Alogliptin Impurity 64 (CAS 1485536-93-3)
- Alogliptin Impurity 56 (CAS 454713-13-4)
- Alogliptin Impurity 46 (CAS 1430222-06-2)
- Alogliptin Impurity 50 (CAS 1883825-48-6)
- Alogliptin Impurity 44-d3 (CAS 1794937-18-0)
- Alogliptin Impurity 31 (CAS 1353254-15-5)
- Alogliptin Impurity 17 (CAS 865758-96-9)
Recommended Standards
- Regorafenib Impurity 80 (CAS CATO-C4X-104780)
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- Mirogabalin Impurity N76 (CAS CATO-CP155176)
- Atorvastatin Impurity 52 (CAS 42558-54-3)
- Loxoprofen Impurity 130 (CAS 261521-19-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com