Edoxaban Impurity 48 CAS 143150-92-9
| CAS No. | 143150-92-9 |
| Molecular Formula | C7H9BrN2S |
| Molecular Weight | 233.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Edoxaban Impurity 48.
Edoxaban Impurity 48 (CAS 143150-92-9) is a certified pharmaceutical impurity reference standard with the molecular formula C7H9BrN2S and a molecular weight of 233.13 g/mol.
Edoxaban Impurity 48 (C7H9BrN2S) contains a nitrile group, sulfur-containing functionality, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Edoxaban Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9BrN2S |
| Molecular Weight | 233.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban Impurity 105 (CAS 2803477-33-8)
- Edoxaban Impurity 34 (CAS 1700085-03-5)
- Edoxaban Impurity 77 (CAS CATO-C4X-106377)
- Edoxaban Impurity 93 (CAS 349125-08-2)
- Edoxaban Impurity 112 (CAS CATO-C4X-1063112)
- Edoxaban Impurity 98 (CAS 365997-32-6)
- Edoxaban Impurity 107 (CAS CATO-C4X-1063107)
- Edoxaban Impurity 113 (CAS CATO-C4X-1063113)
Recommended Standards
- 3-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy 4-Bromomethyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy 76893-32-8 (CAS 76893-32-8)
- N1-(2,6-Dichlorobenzyl)-N1-methylethane-1,2-diamine (CAS 1096873-43-6)
- 51694-22-5 2-Nitrophenyl selenocyanic acid o-Nitrophenyl selenocyanate Selenocyanic acid, 2-nitrophenyl ester AI3-62902 EINECS 257-350-4 2-Nitrophenyl selenocyanate (CAS 51694-22-5)
- N1-(2,4-dichlorobenzyl)-N1-methylethane-1,2-diamine (CAS 1096873-47-0)
- Procaterol Impurity 52 (CAS CATO-C4X-181052)
- Desloratadine impurity 66 (CAS CATO-C4X-143066)
- Adefovir Disoproxil Dimer Impurity (CAS CATO-C4X-115226)
- 3-[2-(2,4-Dibromophenoxy)ethyl]piperidinehydrochloride (CAS 1219957-61-5)
- Tegoprazan impurity 37 (CAS CATO-C4X-229737)
- 5-(Difluoromethyl)-2-methylbenzonitrile (CAS 1261618-13-6)
- 7-Methoxy-3-nitroquinoline (CAS 39977-95-2)
- 2-(3-iodo-1-bicyclo[1.1.1]pentanyl)acetamide (CAS 2242694-00-2)
- Methyl 2-bromo-4-fluoro-5-methylbenzoate (CAS 1437780-13-6)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
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