2-Bromo-5-(trifluoromethyl)thiophene CAS 143469-22-1
| CAS No. | 143469-22-1 |
| Molecular Formula | C5H2BrF3S |
| Molecular Weight | 231.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Bromo-5-(trifluoromethyl)thiophene (CAS 143469-22-1) is a high-purity analytical reference standard with the molecular formula C5H2BrF3S and a molecular weight of 231.03 g/mol.
2-Bromo-5-(trifluoromethyl)thiophene (C5H2BrF3S) contains sulfur-containing functionality, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-Bromo-5-(trifluoromethyl)thiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2BrF3S |
| Molecular Weight | 231.03 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
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- Diethyl (aminomethyl)phosphonate (CAS 50917-72-1)
- Tert-butyl (2-chloro-3-(2-hydroxyethyl)pyridin-4-yl)carbamate (CAS 494767-21-4)
- Methyl Phenyl Malonate (CAS 53439-79-5)
- tert-Butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine-1-carboxylate (CAS 717900-74-8)
- 2-Bromo-4-chloro-6-methylpyridine (CAS 1206249-38-8)
- N-Desmethyl 3-Hydroxy Mepivacaine (CAS 247061-17-2)
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