Olmesartan Impurity 12 CAS 144690-92-6
| CAS No. | 144690-92-6 |
| Molecular Formula | C48H44N6O6 |
| Molecular Weight | 800.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Olmesartan Impurity 12 (CAS 144690-92-6) is a certified pharmaceutical impurity reference standard with the molecular formula C48H44N6O6 and a molecular weight of 800.90 g/mol.
Olmesartan Impurity 12 (C48H44N6O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H44N6O6 |
| Molecular Weight | 800.90 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 6 |
Related Olmesartan Standards
- Olmesartan EP impurity D (CAS 1020157-01-0)
- Olmesartan Impurity 82 (CAS CATO-C4X-109782)
- Olmesartan Impurity 113 (CAS CATO-C4X-1097113)
- Olmesartan Impurity 52 (CAS 1040405-56-8)
- Olmesartan Impurity 100 (CAS CATO-C4X-1097100)
- Olmesartan Impurity 95 (CAS CATO-C4X-109795)
- Olmesartan Impurity 101 (CAS CATO-C4X-1097101)
- Olmesartan Impurity 40 (CAS 1227626-51-8)
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