2,2,2-Trifluoro-1-[4-(trifluoromethyl)-3-indolyl]ethanone CAS 1448890-70-7
| CAS No. | 1448890-70-7 |
| Molecular Formula | C11H5F6NO |
| Molecular Weight | 281.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,2,2-Trifluoro-1-[4-(trifluoromethyl)-3-indolyl]ethanone (CAS 1448890-70-7), molecular formula C11H5F6NO and molecular weight 281.15 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H5F6NO, 2,2,2-Trifluoro-1-[4-(trifluoromethyl)-3-indolyl]ethanone contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 281.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H5F6NO |
| Molecular Weight | 281.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- 2,2,2-Trifluoro-N,N-dihexylacetimidamide (CAS 1510-54-9)
- Methyl 2-((3,3,3-trifluoro-2-hydroxypropyl)thio)benzoate (CAS 385383-55-1)
- 2,2,2-Trifluoro-1-(4'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 134249-43-7)
- 2,2,2-Trifluoro-1-(3'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 1443306-54-4)
- 2,2,2-Trifluoro-1-(2'-methoxy-[1,1'-biphenyl]-4-yl)ethanone (CAS 1443331-45-0)
- 2,2,2-Trifluoro-1-(2'-methoxy-[1,1'-biphenyl]-3-yl)ethan-1-one (CAS 1443332-13-5)
- 2,2,2-Trifluoro-1-(3'-methoxy-[1,1'-biphenyl]-3-yl)ethanone (CAS 1443341-43-2)
- 4,4,4-Trifluoro-3-methylbutan-1-ol (CAS 339-62-8)
Recommended Standards
- 5-Bromo-2-(tert-butyl)phthalazin-1(2H)-one (CAS 1443286-58-5)
- 4-Bromocyclohex-3-en-1-yl benzoate (CAS 1450812-66-4)
- 6-Bromo-2-(pyrrolidin-3-yl)isoindolin-1-one (CAS 1443285-83-3)
- 1-(7-Bromo-5-methylbenzofuran-2-yl)butan-1-one (CAS 1485915-46-5)
- 4-Chloro-6-fluoro-2-(trifluoromethyl)quinoline-3-carbonitrile (CAS 1263286-10-7)
- Bis(methylsulfinylethyl)sulfone (CAS 137371-96-1)
- Fmoc-Gln(Trt)-Ser(Psi(Me,Me)pro)-OH (CAS 1821378-64-6)
- (S)-3,3,3-trifluoro-2-hydroxy-2-phenylpropanoic acid (CAS 29246-94-4)
- 2-(2,3-Dichlorophenoxy)-N'-(furan-2-ylmethylene)acetohydrazide (CAS 477731-47-8)
- 2-(Difluoromethyl)-3-iodo-6-methoxypyridine-4-carboxylic acid (CAS 1807020-24-1)
- 3-[(1-benzylpiperidin-4-yl)(methyl)amino]propan-1-ol (CAS 778568-73-3)
- Trametinib impurity 02 (CAS 871700-32-2)
- 2-(4-(Piperidin-1-yl)butoxy)benzaldehyde (CAS 82625-42-1)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
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