Tolvaptan Impurity 24 CAS 150683-27-5
| CAS No. | 150683-27-5 |
| Molecular Formula | C25H23ClN2O3 |
| Molecular Weight | 434.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 434.91 g/mol gives Tolvaptan Impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tolvaptan Impurity 24 (CAS 150683-27-5) is a certified pharmaceutical impurity reference standard with the molecular formula C25H23ClN2O3 and a molecular weight of 434.91 g/mol.
Tolvaptan Impurity 24 (C25H23ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tolvaptan Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H23ClN2O3 |
| Molecular Weight | 434.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 23 (CAS 1580889-33-3)
- Tolvaptan Impurity 41 (CAS 1580889-32-2)
- Tolvaptan Impurity 99 (CAS 137977-35-6)
- Tolvaptan Impurity 40 (CAS 176970-21-1)
- Tolvaptan Impurity 14 (CAS 137973-76-3)
- Tolvaptan Impurity 67 (CAS 1580889-26-4)
- Tolvaptan Impurity 68 (CAS 1580889-24-2)
- Tolvaptan Impurity 91 (CAS CATO-C4X-195591)
Recommended Standards
- Sotagliflozin Impurity 8 (CAS CATO-C4X-30048)
- 5383-17-5 (CAS 5383-17-5)
- 1112429-00-1 BS-8381 N-[2-(4-chlorophenyl)ethyl]-1-{8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl}piperidine-4-carboxamide (CAS 1112429-00-1)
- Methyl D-phenylalanylglycinate (CAS 5184-18-9)
- Desmethyl Fluorometholone (CAS 426-20-0)
- Alogliptin Impurity 57 (CAS 4270-27-3)
- Elagolix Impurity 112 (CAS CATO-C4X-2068112)
- tert-butyl 3-(trifluoromethoxy)pyrrolidine-1-carboxylate (CAS 1206523-91-2)
- Argatroban Impurity 20 (CAS 78306-52-2)
- tert-butyl N-[(1S)-1-ethyl-2-oxo-propyl]carbamate (CAS 304021-05-4)
- 3-Methyl-1-(4-methylcyclohexyl)-1h-pyrazole-4-carboxylic acid (CAS 1342460-16-5)
- 7-Bromo-3-chloro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (CAS 917878-65-0)
- N,N-Didesethyl Sunitinib-d4 Hydrochloride (CAS 1346606-30-1)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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