Omarigliptin Impurity 4 CAS 1456616-42-4
| CAS No. | 1456616-42-4 |
| Molecular Formula | C16H19F2NO4 |
| Molecular Weight | 327.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Omarigliptin Impurity 4 (CAS 1456616-42-4), a pharmacopoeial impurity reference standard (molecular formula C16H19F2NO4, MW 327.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Omarigliptin Impurity 4 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Omarigliptin Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19F2NO4 |
| Molecular Weight | 327.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Omarigliptin Standards
- Omarigliptin Impurity 3 (CAS 951127-25-6)
- Omarigliptin Impurity 5 (CAS 1456616-44-6)
- Omarigliptin Impurity 6 (CAS 1456616-43-5)
- Omarigliptin Impurity 7 (CAS CATO-C4X-11477)
- Omarigliptin Impurity 8 (CAS CATO-C4X-11478)
- Omarigliptin Impurity 2 (CAS 1172623-99-2)
- Omarigliptin Impurity 16 (CAS 1819364-01-6)
- Omarigliptin Impurity 1 (CAS 1172623-98-1)
Recommended Standards
- 338409-45-3 5-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl cyclopropanecarboxylate KS-00001VFH (CAS 338409-45-3)
- N2-(Prop-2-en-1-yl)-5-[3-(trifluoromethyl)benzoyl]-1,3-thiazole-2,4-diamine (CAS 339020-05-2)
- 3-Nitro-4-((1-phenyl-1H-tetrazol-5-yl)thio)benzaldehyde (CAS 461439-08-7)
- 3-(Trifluoromethyl)benzyl 2-(methylthio)nicotinate (CAS 485370-72-7)
- Axitinib Impurity 78 (CAS CATO-C4X-107178)
- Bivalirudin Impurity 13 (CAS CATO-C4X-144813)
- Paricalcitol lmpurity 41 (CAS CATO-C4X-138741)
- 1-(5-(1-Ethyl-1H-pyrazol-5-yl)-1,2,4-oxadiazol-3-yl)-N-methylmethanamine (CAS 1707562-47-7)
- 2-Hydrazinylquinoxaline (CAS 61645-34-9)
- 7-(3-((2-Cyclohexyl-2-oxoethylidene)amino)-2,5-dioxoimidazolidin-4-yl)heptanoic acid (CAS 94125-79-8)
- N-(5-(1H-Pyrrol-1-yl)quinolin-6-yl)acetamide (CAS 88328-41-0)
- 2-Bromo-3-(difluoromethyl)-6-methylpyridin-4-amine (CAS 1805259-64-6)
- N-(4-Iodophenyl)benzamide (CAS 52807-29-1)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com